Wim H van Zwam
Wim H van Zwam


Medical study, MD (Free University, Amsterdam)
Tropical Medicine (Dutch Tropical Institute, Amsterdam)
Radiology (Maastricht University Medical Centre)
International Diplome in Neurovascular Diseases, MSc (Université Paris XI)

Positions and Employment

Resident Tropical Medicine (Surgery - Gynaecology)
Slotervaart General Hospital, Amsterdam
1989 - 1992
Tropical Doctor, Medecins Sans Frontieres
SomaliŽ, Laos, Sri Lanka
1992 - 1994
Resident Radiology, MUMC+, Maastricht
1995 - 2002
Interventional Radiology, Leuven, Belgium
Neuro-interventional Radiology, Tilburg
Neuro-interventional Radiology, Essen, Germany
Interventional Radiology, MUMC+, Maastricht
2003 -

Other Experience and Professional Memberships

Thesis, PhD: 2013
Aneurysmal subarachnoid hemorrhage: Imaging strategies and cost-effectiveness aspects in diagnostic work-up and post-therapeutic follow-up

PI of MACCA study (Magnetic resonance Angiography with Contrast in patients with Cerebra Aneurysms)
Funding: 300k Euro from Profileringsfonds azM. - 2006-2010

Professional memberships: NVvR, NGIR, NNG, NVF, ESR, CIRSE, ESMINT, WFITN

Reviewer for two journals.

Co-PI, member of executive committee and imaging committee of the MRCLEAN trial (Multicenter Randomized Clinical trial of Endovascular treatment of Acute ischemic stroke in the Netherlands)
Funding: 800k Euro from Dutch Heart Foundaton; 500k Euro from unrestricted grants

PI of MRCLEAN_Late (MRCLEAN - patients arriving between 6 - 12 hrs after symptom onset)

Selected peer-reviewed publications

  • Berkhemer OA?. van Zwam WH,? Dippel D. A randomized trial of intra-arterial treatment of acute ischemic stroke. NEJM 2015. (shared last author)
  • Goyal M, Menon BK, van Zwam WH,?., Jovin TG; HERMES collaborators. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual data from five randomized trials. Lancet 2016:387:1723-31 (shared first author)
  • Sailer AM, van Zwam WH, Wildberger JE, Grutters JP.: Cost-effectiveness modelling in diagnostic imaging: a stepwise approach. Eur Radiol. 2015 May 24. DOI 10.1007/s00330-015-3770-8
  • Sailer AM, Wagemans BA, Nelemans PJ, de Graaf R, van Zwam WH: Diagnosing intracranial aneurysms with MR angiography: systematic review and meta-analysis. Stroke. 2014 Jan;45(1):119-26.
  • Sailer AM, Grutters JP, Wildberger JE, Hofman PA, Wilmink JT, van Zwam WH: Cost-effectiveness of CTA, MRA and DSA in patients with non-traumatic subarachnoid haemorrhage. Insights Imaging. 2013 Aug;4(4):499-507.
  • Santos EM, Marquering HA, Berkhemer OA, van Zwam WH, van der Lugt A, Majoie CB, Niessen WJ; MR CLEAN investigators: Development and validation of intracranial thrombus segmentation on CT angiography in patients with acute ischemic stroke. PLoS One. 2014 Jul 17;9(7):e101985.
  • Willem H van Zwam, Paul Hofman, Alfons Kessels, et al: Diagnostic performance of contrast enhanced magnetic resonance angiography in detecting intracranial aneurysms in patients presenting with subarachnoid haemorrhage. EJMINT Original Article, 2012: 1240000078 (4th October 2012)
  • Fransen PS, Berkhemer OA, ?, van Zwam WH, Roos YB, van Oostenbrugge RJ, Majoie CB, van der Lugt A, Dippel DW; Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands (MR CLEAN) investigators. Time to Reperfusion and Treatment Effect for Acute Ischemic Stroke: A Randomized Clinical Trial. JAMA Neurol 2016;73:190-6
  • Tijssen MP, Hofman PA, Stadler AA, van Zwam WH, de Graaf R, van Oostenbrugge RJ, Klotz E, Wildberger JE, Postma AA: The role of dual energy CT in differentiating between brain haemorrhage and contrast medium after mechanical revascularisation in acute ischaemic stroke. Eur Radiol. 2014 Apr;24(4):834-40
  • Klompenhouwer EG, Dings JT, van Oostenbrugge RJ, Oei S, Wilmink JT, van Zwam WH: Single-center experience of surgical and endovascular treatment of ruptured intracranial aneurysms. AJNR Am J Neuroradiol. 2011 Mar;32(3):570-5