PI of MACCA study (Magnetic resonance Angiography with Contrast in patients with Cerebra Aneurysms)
Funding: 300k Euro from Profileringsfonds azM. - 2006-2010
Professional memberships: NVvR, NGIR, NNG, NVF, ESR, CIRSE, ESMINT, WFITN
Reviewer for two journals.
Co-PI, member of executive committee and imaging committee of the MRCLEAN trial (Multicenter Randomized Clinical trial of Endovascular treatment of Acute ischemic stroke in the Netherlands)
Funding: 800k Euro from Dutch Heart Foundaton; 500k Euro from unrestricted grants
PI of MRCLEAN_Late (MRCLEAN - patients arriving between 6 - 12 hrs after symptom onset)
Selected peer-reviewed publications
Berkhemer OA?. van Zwam WH,? Dippel D. A randomized trial of intra-arterial treatment of acute ischemic stroke. NEJM 2015. (shared last author)
Goyal M, Menon BK, van Zwam WH,?., Jovin TG; HERMES collaborators. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual data from five randomized trials. Lancet 2016:387:1723-31 (shared first author)
Sailer AM, van Zwam WH, Wildberger JE, Grutters JP.: Cost-effectiveness modelling in diagnostic imaging: a stepwise approach. Eur Radiol. 2015 May 24. DOI 10.1007/s00330-015-3770-8
Sailer AM, Wagemans BA, Nelemans PJ, de Graaf R, van Zwam WH: Diagnosing intracranial aneurysms with MR angiography: systematic review and meta-analysis. Stroke. 2014 Jan;45(1):119-26.
Sailer AM, Grutters JP, Wildberger JE, Hofman PA, Wilmink JT, van Zwam WH: Cost-effectiveness of CTA, MRA and DSA in patients with non-traumatic subarachnoid haemorrhage. Insights Imaging. 2013 Aug;4(4):499-507.
Santos EM, Marquering HA, Berkhemer OA, van Zwam WH, van der Lugt A, Majoie CB, Niessen WJ; MR CLEAN investigators: Development and validation of intracranial thrombus segmentation on CT angiography in patients with acute ischemic stroke. PLoS One. 2014 Jul 17;9(7):e101985.
Willem H van Zwam, Paul Hofman, Alfons Kessels, et al: Diagnostic performance of contrast enhanced magnetic resonance angiography in detecting intracranial aneurysms in patients presenting with subarachnoid haemorrhage. EJMINT Original Article, 2012: 1240000078 (4th October 2012)
Fransen PS, Berkhemer OA, ?, van Zwam WH, Roos YB, van Oostenbrugge RJ, Majoie CB, van der Lugt A, Dippel DW; Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands (MR CLEAN) investigators. Time to Reperfusion and Treatment Effect for Acute Ischemic Stroke: A Randomized Clinical Trial. JAMA Neurol 2016;73:190-6
Tijssen MP, Hofman PA, Stadler AA, van Zwam WH, de Graaf R, van Oostenbrugge RJ, Klotz E, Wildberger JE, Postma AA: The role of dual energy CT in differentiating between brain haemorrhage and contrast medium after mechanical revascularisation in acute ischaemic stroke. Eur Radiol. 2014 Apr;24(4):834-40
Klompenhouwer EG, Dings JT, van Oostenbrugge RJ, Oei S, Wilmink JT, van Zwam WH: Single-center experience of surgical and endovascular treatment of ruptured intracranial aneurysms. AJNR Am J Neuroradiol. 2011 Mar;32(3):570-5